Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.800 GenomicAlterations disease CGI
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.600 GenomicAlterations disease CGI
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4 		0.600 GenomicAlterations disease CGI
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.600 GenomicAlterations disease CGI
Entrez Id: 208
Gene Symbol: AKT2
AKT2 		0.400 GenomicAlterations disease CGI
Entrez Id: 324
Gene Symbol: APC
APC 		0.400 GenomicAlterations disease CGI
Entrez Id: 6416
Gene Symbol: MAP2K4
MAP2K4 		0.360 GenomicAlterations disease CGI
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.800 CausalMutation disease CGI
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.800 CausalMutation disease CGI
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.800 CausalMutation disease CLINVAR Nonsense-mediated mRNA decay: terminating erroneous gene expression. 15145354 2004
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4 		0.600 CausalMutation disease CGI
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.600 CausalMutation disease CGI
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.600 CausalMutation disease CGI
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.600 CausalMutation disease CGI
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.600 CausalMutation disease CGI
Entrez Id: 2033
Gene Symbol: EP300
EP300 		0.510 CausalMutation disease CGI
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		0.500 CausalMutation disease CLINVAR
Entrez Id: 324
Gene Symbol: APC
APC 		0.400 CausalMutation disease CGI
Entrez Id: 6416
Gene Symbol: MAP2K4
MAP2K4 		0.360 CausalMutation disease CGI
Entrez Id: 54894
Gene Symbol: RNF43
RNF43 		0.310 CausalMutation disease CGI
Entrez Id: 5932
Gene Symbol: RBBP8
RBBP8 		0.300 CausalMutation disease CGI
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.800 AlteredExpression disease BEFREE Having pancreatic cancer with tumoral loss of ATM and normal TP53 protein expression is associated with a poorer prognosis. 24486587 2014
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.800 AlteredExpression disease BEFREE Clinicopathological significance of abnormalities in Gadd45 expression and its relationship to p53 in human pancreatic cancer. 12171884 2002
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.800 AlteredExpression disease BEFREE Both failed to specifically suppress p53 protein production in a cell-free assay system or to have any effect on mutant p53 expression by human pancreatic cancer cell lines. 7880719 1995
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.800 AlteredExpression disease BEFREE Taken together, our data indicate that PRIMA-1 induces apoptosis in p53 mutant pancreatic cancer cells by promoting the re-activation of p53 and inducing proapoptotic signaling pathways, providing in vitro evidence for a potential therapeutic approach in pancreatic cancer. 24838627 2014